A Comparative Study between Delineation of Radiotherapy Target Volumes with and Without Peritumoral Edema for Patients with Postoperative Glioblastoma Multiforme
Abstract
Background: Glioblastoma Multiforme (GBM) is an aggressive primary brain tumor with a poor prognosis. Radiotherapy is a critical component of GBM treatment, but the optimal delineation of the clinical target volume (CTV), particularly regarding the inclusion of peritumoral edema, remains debated. This study aimed to compare the clinical outcomes and toxicities in GBM patients treated with radiotherapy that includes or excludes peritumoral edema in the CTV.