Primary Biliary Cholangitis in A Male Patient: A Case Report
Abstract
Primary biliary cholangitis (PBC) is a chronic autoimmune
cholestatic liver disease characterized by progressive
destruction of small intrahepatic bile ducts. It predominantly
affects middle-aged women, and occurrence in males is
uncommon. We report a case of a 53-year-old male presenting
with long-standing pruritus, recent onset jaundice, and pedal
edema. Laboratory evaluation revealed markedly elevated
alkaline phosphatase, positive antinuclear antibody (ANA),
and antimitochondrial antibody (AMA) with negative viral
markers and no evidence of biliary obstruction on imaging.