Salivary Biomarker in Diagnosis of Oral Squamous Cell Carcinoma: A Scoping Review
Abstract:
Oral saliva is an extracellular fluid produced and secreted
by salivary glands which contains 99% of water and 1% of
organic and inorganic substances. Inorganic elements
consist of minerals such as sodium, potassium, calcium,
magnesium, fluoride, and phosphates. Organic elements
comprise enzymes, hormones, immunoglobulins,
antioxidants are present in the saliva. The recent findings
suggest that saliva could be used as a biomarker in
diagnosing oral cancer and pre cancer. Most oral cancers
are oral squamous cell carcinomas. Using saliva for detection
of early oral squamous cell carcinomas in the search for new
clinical markers is a promising approach because of its
noninvasive sampling and easy collection method.
.